Herman Branson: physicist, best known for his research on the alpha helix protein structure



Herman Russell Branson (August 14, 1914 – June 26, 1995) was an African-American physicist, best known for his research on the alpha helix protein structure, and was also the president of two colleges.

Early life

Branson received his B.S. from Virginia State College in 1936, and his Ph.D. in physics from the University of Cincinnati, under the direction of Boris Padowski, in 1939. After a stint at Dillard University, he joined Howard University in 1941 as an assistant professor of physics and chemistry. He remained at Howard for 27 years, achieving increasingly important positions, eventually becoming head of the physics department, director of a program in experimental science and mathematics, and working on the Office of Naval Research and Atomic Energy Commission Projects in Physics at Howard University.

Work on protein structure

In 1948, Branson took a leave and spent time at the California Institute of Technology, in the laboratory of the chemist Linus Pauling. There he was assigned work on the structure of proteins, specifically to use his mathematical abilities to determine possible helical structures that would fit both the available X-raycrystallography data and a set of chemical restrictions outlined by Pauling. After some months of work, Branson handed in a report narrowing the possible structures to two helixes, a tighter coil Pauling termed “alpha,” and a looser helix called “gamma.” Branson then returned to Howard to work on other projects. Some months later he received a letter from Pauling along with a draft manuscript of a paper detailing the two helixes, with Branson listed as third author (after Pauling and his assistant Robert Corey, the laboratory’s expert in transforming X-ray data into precise models). Pauling asked for suggestions; it is likely that Branson approved the paper as written, although there is no reply on record.

Later career and controversy

Branson went on to a significant career, eventually serving as president of Central State University in Wilberforce, Ohio, from 1968–1970, and then president of Lincoln University until his retirement in 1985. He was active in increasing federal funding for higher education, and helped found the National Association for Equal Opportunity in Higher Education in 1969.

In 1984 Branson wrote Pauling biographers Victor and Mildred Goertzel implying that his contribution to the alpha helix had been greater than the final paper indicated. “I took my work to Pauling who told me that he thought they [the proposed alpha and gamma helixes] were too tight, that he thought that a protein molecule should have a much larger radius so that water molecules could fit down inside and cause the protein to swell,” he wrote. “I went back and worked unsuccessfully to find such a structure.” When he received Pauling’s note with the draft manuscript, Branson wrote, “I interpreted this letter as establishing that the alpha and gamma in my paper were correct and that the subsequent work done was cleaning up or verifying. The differences were nil.” He added in his letter to the Goertzels that he “resented” the later attention lavished on Pauling and Corey. The conservative watchdog group Accuracy in Media referred to the incident in an attack on Pauling in 1994 The available records, historical context, knowledge of the personalities involved, and studies of Pauling’s laboratory and methods at the time have led most historians to accord greater credit to Pauling and Corey.



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