James Derham[1] (May 2, 1762[2]—1802?), also known as James Durham,[3] was the first African American to formally practice medicine in the United States,[4] though he never received an M.D. degree.

James Derham was born into slavery in Philadelphia in 1762. As a child, Derham was transferred to Dr. John Kearsley Jr. under whom Derham studied medicine. From Dr. Kearsley, Derham learned about compound medicine with a focus on curing illnesses of the throat,[3] as well as patient bedside manner.[5] Upon Dr. Kearsley’s death, Derham, then fifteen years old,[3] was moved between several different masters before finally settling with Dr. George West, a surgeon for a British regiment during the American Revolutionary War. He was eventually transferred again, this time to New Orleans doctor Robert Dove. As an assistant at Dove’s practice, Derham and Dove became friends, and Dove eventually granted Derham his freedom. With some financial assistance from Dove, Derham opened his own medical practice in New Orleans.[5] By 1789, his practice is reported to have made about $3,000 annually.[6] In 1788, Derham and Dr. Benjamin Rush met each other in Philadelphia, and corresponded with one another for twelve years. Derham’s final letter to Rush in 1802 is the last record of his existence. It is believed that after the Spanish authorities restricted Derham to treating throat diseases in 1801, Derham left his practice in New Orleans.


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